[Basic directions in pathologoanatomic diagnosis of human tumors]

The paper deals with basic lines in the development of oncomorphology, such as electron microscopy, immunohistochemistry, and telepathology. Under the present conditions, a pathologist's capacities to diagnose tumors and to elucidate their histogenesis are shown to be greatly expanded due to advances in genetics, immunology, and a number of other biological disciplines. Introduction of methods of molecular pathology can establish a relationship of multiple primary tumors of the similar histological structure of both nodes, predict a disease, and define drug tumor sensitivity. The above shows an increasing role of pathologists in diagnosis and choice of treatments in cancer patients. The author presents his experience in these areas as a practical cancer pathologist at the Department of Pathology, N. N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences.