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Updated: Aug 8, 2026

Induction of Invasive Transitional Cell Bladder Carcinoma in Immune Intact Human MUC1 Transgenic Mice: A Model for Immunotherapy Development
Published on: October 31, 2013
ImmunoCyt a useful method in the follow-up protocol for patients with urinary bladder carcinoma
1Department of Clinical Pathology, Borås Central Hospital, Sweden.
Objective:
To evaluate the ImmunoCyt test--a urine-bound test for the detection of malignant transitional cells.
Patients And Methods:
ImmunoCyt was compared with the standard investigation at our hospital for bladder cancer--cystoscopy, cytological examination of bladder wash material and, if necessary, a histological examination. A voided urine sample was collected before cystoscopy. We investigated 121 patients; seven specimens could not be evaluated.
Results:
Thirty-one of the 114 patients had a histologically proven urinary bladder carcinoma. All 31 cases were positive in the ImmunoCyt test. Twenty-six of the 83 negative cases were ImmunoCyt positive. The sensitivity was 100% and the specificity was 68.7%.
Conclusion:
ImmunoCyt is easily applicable in a small laboratory and has high sensitivity and acceptable specificity.
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