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Transcriptional silencing: replication redux
1Department of Molecular Biology, Sciences II, University of Geneva, 30 quai Ernest-Ansermet, CH-1211, 4, Geneva, Switzerland.
Current Biology : CB
|October 26, 2001
Abstract:
Recent studies indicate that, contrary to long-held belief, DNA replication does not have a direct role in transcriptional silencing, but progression through S phase of the cell cycle is nevertheless required for the establishment of silent chromatin.