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Updated: Aug 5, 2026

Assessment of Lymphocyte Migration in an Ex Vivo Transmigration System
Published on: September 20, 2019
T-cell subpopulations in the development of atopic and contact allergy
G Girolomoni1, S Sebastiani, C Albanesi
1Laboratory of Immunology, Istituto Dermopatico dell'Immacolata, IRCCS, Via Monti di Creta 104, 00167, Roma, Italy. giro@idi.it
Abstract:
Remarkable progress has been made in our understanding of the pathogenesis of skin diseases mediated by T cells. T-cell subsets responsible for the expression and regulation of allergic contact dermatitis to small chemicals or 'haptens' have been defined further, and the dynamics of T cells involved in the pathogenesis of atopic dermatitis have been clarified. In addition, studies are beginning to reveal the important contribution of skin resident cells to atopic dermatitis and the underlying molecular mechanisms.
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