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Updated: Aug 6, 2026
10:58
Protein WISDOM: A Workbench for In silico De novo Design of BioMolecules
Published on: July 25, 2013
Design and synthesis of potent and selective inhibitors of integrin VLA-4
S Wattanasin1, B Weidmann, D Roche
1Novartis Institute for Biomedical Research, Novartis Pharmaceuticals Corporation, 556 Morris Avenue, Summit, NJ 07901, USA. sompong.wattanasin@pharma.novartis.com
Bioorganic & Medicinal Chemistry Letters
|October 26, 2001
Abstract:
The synthesis and identification of a novel series of inhibitors of integrin VLA-4 are described. Their in vitro activity and selectivity against closely related integrins are also presented.
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