Related Experiment Video

Updated: Oct 3, 2026

Surgical Induction of Endolymphatic Hydrops by Obliteration of the Endolymphatic Duct
11:49

Surgical Induction of Endolymphatic Hydrops by Obliteration of the Endolymphatic Duct

Published on: January 22, 2010

Ménière's disease and delayed endolymphatic hydrops in children

K Mizukoshi1, H Shojaku, S Aso

  • 1Health Services Facility for the Aged Amenity Nobukiyo, Toyama, Japan.

Acta Oto-Laryngologica. Supplementum
|October 27, 2001
PubMed

Insights

Pediatric Ménière

Area of Science:

  • Otolaryngology
  • Neurotology
  • Pediatric Neurology

Background:

  • Endolymphatic hydrops disorders, including Ménière's disease (MD) and delayed endolymphatic hydrops (DEH), are typically diagnosed in adults.
  • Pediatric cases are rare, necessitating further characterization.

Purpose of the Study:

  • To investigate the clinical characteristics of pediatric patients with endolymphatic hydrops.
  • To identify specific features distinguishing pediatric MD and DEH.

Main Methods:

  • Retrospective analysis of 7418 patients from 1979-1999.
  • Selection of 5 pediatric MD and 3 pediatric DEH patients.
  • Evaluation of clinical features, audiological tests, and electrophysiological findings.

Main Results:

  • Pediatric MD constituted only 1.5% of all MD cases.
  • Key findings in pediatric MD included fluctuating hearing loss, positive glycerol and furosemide tests, and a high SP/AP ratio.
  • Two pediatric MD patients experienced prolonged vertigo and underwent surgery.
  • Ipsilateral DEH was observed in 2/3 of pediatric DEH patients, with contralateral in 1/3.

Conclusions:

  • Pediatric endolymphatic hydrops disorders present unique clinical characteristics.
  • Early identification and characterization are crucial for appropriate management of pediatric MD and DEH.

More Related Videos

Surgical Treatment of an Endolymphatic Sac Tumor04:34

Surgical Treatment of an Endolymphatic Sac Tumor

Published on: May 26, 2023

Endolymphatic Duct Blockage as a Surgical Treatment Option for Ménière's Disease04:11

Endolymphatic Duct Blockage as a Surgical Treatment Option for Ménière's Disease

Published on: April 28, 2023

Related Concept Videos

Lysosomal Hydrolases01:22

Lysosomal Hydrolases

Lysosomes are the site for the degradation of macromolecules and biological polymers released during membrane trafficking events such as secretory, endocytic, autophagic, and phagocytic pathways. The membrane-enclosed area of the lysosome, called the lumen, contains hydrolytic enzymes active in an acidic environment. These acid hydrolases are functional at a pH between 4.5 and 5 and are involved in cellular processes such as cell signaling, energy metabolism, restoration of the plasma membrane,...
Encephalitis l: Introduction01:19

Encephalitis l: Introduction

Encephalitis is inflammation of the brain parenchyma, most often due to infections or autoimmune processes. It presents with neuropsychiatric features such as fever, altered mental status, behavioral changes, cognitive dysfunction, seizures, focal deficits, and sometimes autonomic instability. In some cases, the meninges are also involved, resulting in meningoencephalitis.Infectious CausesInfectious encephalitis is most commonly viral but can also result from bacterial, fungal, or parasitic...
Cytomegalovirus Disease01:27

Cytomegalovirus Disease

Cytomegalovirus (CMV) disease is caused by human cytomegalovirus, a double-stranded DNA virus of the Herpesviridae family. While primary CMV infection is often asymptomatic in immunocompetent individuals, the virus can cause severe disease in neonates and immunocompromised patients. CMV is the most common cause of congenital viral infection in the United States, and a major pathogen in solid organ and hematopoietic stem cell transplant recipients.CMV is transmitted via bodily fluids, sexual...