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Exploring Independent Effects of Follicle-Stimulating Hormone In Vivo in a Mouse Model
Published on: August 11, 2023
Potential dangers in the customary methods of conducting meta-analyses. Recombinant versus urinary follicle
1Thorpes, The Grip, Linton, Cambridge CB1 6NR, UK. dew1@cus.cam.ac.uk
Human Reproduction (Oxford, England)
|October 27, 2001
Abstract:
The customary method of combining success rates in meta-analyses may often result in serious biases, leading to erroneous inferences. This arises because of an inadmissible pooling of frequencies from heterogeneous sources. The fundamental statistical principle, that the magnitude of an 'effect' should always be tested against the variation in that effect over the sample, may not therefore be satisfied. A simple, but rigorous, alternative method is described.