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Prevalence and risk factors of adenomyosis at hysterectomy
T Bergholt1, L Eriksen, N Berendt
1Department of Obstetrics and Gynaecology, Gentofte University Hospital, Niels Andersens Vej 65, 900 Hellerup, Denmark. tbe@dadlnet.dk
Background:
The present study was performed to evaluate the prevalence and possible associated risk factors for adenomyosis.
Methods:
Medical records were retrieved and histo-pathological material re-examined for 549 consecutive women undergoing hysterectomy in a two-year period from 1990-1991.
Results:
The prevalence of adenomyosis in the study varied from 10.0-18.2%, depending on different diagnostic criteria. The presence of endometrial hyperplasia at the time of hysterectomy was the only variable significantly associated with adenomyosis (OR = 3.0; 95% CI: 1.2-8.3). No statistically significant association was found between adenomyosis and previous caesarean section, endometrial curettage or evacuation of the uterus. Furthermore, we did not see any significant association between adenomyosis and pain-related symptoms, indication for hysterectomy, age, parity or number of myometrial samples.
Conclusions:
Our study stresses the need for precise diagnostic criteria for adenomyosis, and furthermore indicates that endometrial hyperplasia and adenomyosis may have a common aetiology.
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