Spondylolisthesis in osteogenesis imperfecta due to pedicle elongation: report of two cases
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Updated: Oct 3, 2026
C-arm-Free Simultaneous OLIF51 and Percutaneous Pedicle Screw Fixation in a Single Lateral Position
Published on: September 16, 2022
P S Basu1, M H Hilali Noordeen, H Elsebaie
1Whittington Hospital, London, UK. parthabasu@lineone.net
Study Design:
Two cases of spondylolisthesis due to severe elongation of pedicles in osteogenesis imperfecta are reported.
Objective:
To describe an unusual type of spondylolisthesis and its successful management.
Summary Of Background Data:
Spondylolisthesis is known to occur in osteogenesis imperfecta. Reports in the literature are few. Pedicle elongation resulting in spondylolisthesis has only been reported once. There is no report of a successful treatment of this type of spondylolisthesis resulting from pedicle elongation.
Method:
Two adolescent girls suffering from osteogenesis imperfecta presented with lower back pain and thoracic scoliosis. One of them had high-grade spondylolisthesis of L3-L4, L4-L5, and L5-S1, with a thoracic scoliosis. She was treated with anterior interbody fusion L3 to sacrum without instrumentation. Later, progression of her scoliosis required combined anterior and posterior instrumented fusion T1 to L1. The other girl presented with L5 spondylolisthesis and thoracic scoliosis. She has back pain as well as neurologic symptoms in her legs and is waiting for surgery.
Results:
At the 3-year follow-up the operated patient is symptom-free from her spine and there has been no progression of either deformity.
Conclusion:
High-grade spondylolisthesis due to elongation of pedicle in osteogenesis imperfecta is uncommon. Anterior interbody fusion of all the involved motion segments has produced good pain relief and arrested deformity progression at the 3-year follow-up.
