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Related Experiment Videos

[Primary pathological changes in cells infected with tick-borne encephalitis virus].

B A Erman, N Ia Pashnina, L S Subbotina

    Tsitologiia
    |January 1, 1975
    PubMed
    Summary

    Tick-borne encephalitis virus infection in pig embryo kidney cells accelerates RNA and protein synthesis. These molecular changes correlate with distinct stages of viral reproduction and release.

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    [Ultrastructural pathology of congenital infection provoked by respiratory viruses].

    Arkhiv patologii·1991

    Area of Science:

    • Molecular Biology
    • Virology
    • Cell Biology

    Context:

    • Tick-borne encephalitis virus (TBEV) infection impacts cellular processes.
    • Understanding TBEV's effect on host cell macromolecules is crucial.

    Purpose:

    • To investigate the synthesis and content of RNA and protein in pig embryo kidney cells post-TBEV infection.
    • To correlate these molecular changes with viral replication.

    Summary:

    • Autoradiography and cytophotometry revealed accelerated RNA synthesis (125-200%) and protein content peaks (123-131%) during TBEV infection.
    • These molecular events, including RNA decrease and virus release at 12 hours, align with viral reproduction phases.

    Impact:

    • Provides insights into the host-pathogen interactions during TBEV infection.

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  • Highlights the dynamic changes in cellular RNA and protein during viral replication.