Related Experiment Video
Updated: Aug 18, 2026

Analysis of AtHIRD11 Intrinsic Disorder and Binding Towards Metal Ions by Capillary Gel Electrophoresis and Affinity Capillary Electrophoresis
Published on: August 22, 2018
Quantitative determination of famotidine through charge-transfer complexation with chloranilic acid
1Department of Pharmaceutical Chemistry, Faculty of Pharmaceutical Sciences, University of Nigeria, Nsukka, Nigeria.
Abstract:
Quantitative determination of famotidine and its dosage forms was carried out spectrophotometrically, analysing the coloured complex resulting from a charge-transfer interaction between the drug as an electron-donor and chloranilic acid as an electron-acceptor. Famotidine-Chloranilic acid complex displayed l-max at 5 25 nm. Conditions and time for complex formation have been optimized. The stoichiometry of the complex is 3:2 donor to acceptor mole ratio. Calibration graph of the complex was found to be linear at a working concentration range of 1.60-11.g% (w/v). Excellent quantitative recoveries (99.01-100.71%) was obtained for the drugs in both its pure and standard dosage forms.
More Related Videos
10:17High-throughput and Comprehensive Drug Surveillance Using Multisegment Injection-Capillary Electrophoresis-Mass Spectrometry
Published on: April 23, 2019
11:44Cellular Membrane Affinity Chromatography Columns to Identify Specialized Plant Metabolites Interacting with Immobilized Tropomyosin Kinase Receptor B
Published on: January 19, 2022
Related Concept Videos
Precipitation Titration: Endpoint Detection Methods
In the Volhard method, a standard excess of AgNO3 is first added to the...
Extraction: Advanced Methods
EDTA: Indirect and Alkalimetric Titration