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Published on: June 11, 2019
The clinical utility of contrast-enhanced 3D MR angiography for cerebrovascular disease
A Okumura1, Y Araki, Y Nishimura
1Department of Neurosurgery, Inuyama Central Hospital, Aichi, Japan.
Insights
Contrast-enhanced 3D MR angiography (CE-MRA) with SmartPrep effectively visualizes cerebrovascular disease. This technique accurately assesses arterial blockages, collateral pathways, and stenosis, offering a reliable, less-invasive imaging option.
Area of Science:
- Radiology
- Neuroimaging
- Vascular Imaging
Background:
- Cerebrovascular diseases require accurate and timely diagnosis.
- Advanced imaging techniques are crucial for evaluating complex arterial anatomy and pathology.
Purpose of the Study:
- To assess the utility of contrast-enhanced 3D MR angiography (CE-MRA) using an automated bolus-detection algorithm (SmartPrep) and specialized coils.
- To evaluate CE-MRA's effectiveness in patients with suspected cerebrovascular disease.
Main Methods:
- Forty-three patients with suspected cerebrovascular events underwent CE-MRA.
- The SmartPrep technique automated gadolinium bolus tracking for triggered, rapid arterial-phase imaging.
- High-resolution imaging covered the craniocervical arteries from the aortic arch to the circle of Willis.
Main Results:
- The SmartPrep technique achieved a 100% successful triggering rate.
- CE-MRA provided selective arterial-phase imaging of carotid and vertebral arteries with minimal venous contamination.
- High-resolution imaging delineated the entire craniocervical arterial tree.
Conclusions:
- CE-MRA with SmartPrep is a highly effective and reliable method for diagnosing cerebrovascular disease.
- This technique accurately evaluates arterial occlusions, collateral circulation, stenosis, and dissection.
- CE-MRA offers a less-invasive alternative for investigating patients with cerebrovascular conditions.
Abstract:
The purpose of this study was to evaluate the usefulness of contrast-enhanced 3D MR angiography (CE-MRA) with an automated bolus-detection algorithm (SmartPrep technique) and the specialized phased-array coils for the patients suspected cerebrovascular disease. Forty-three patients with brain attack were examined with CE-MRA. A tracker volume of SmartPrep technique was placed along the ascending aorta in the coronal image. After the bolus injection of gadolinium, an increase in signal that corresponded to the arrival of gadolinium was used to trigger centric re-ordered spoiled gradient echo arterial selective MRA with imaging time of 20-40 sec. We were able to achieve a 100% successful triggering rate of SmartPrep technique and selectively arterial-phase carotid and vertebral arteries with almost no venous contamination could be delineated. These techniques enabled high resolution imaging of entire craniocervical arteries from aortic arch to the circle of Willis. This CE-MRA was useful to evaluate both occlusion of arteries and the collateral pathways and to measure stenosis and residual flow of dissection accurately. CE-MRA was a reliable less-invasive alternative to investigate the patients of cerebrovascular disease.
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