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ToothPrint, a proteomic database for dental tissues.

M J Hubbard1, M J Faught, B H Carlisle

  • 1Department of Biochemistry, University of Otago, Dunedin, New Zealand. mike.hubbard@stonebow.otago.ac.nz

Proteomics
|October 30, 2001
PubMed
Summary
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ToothPrint is a new proteomic database for dental tissues, offering protein identification and functional data. This resource aids dental biology research by providing accessible proteomic information.

Area of Science:

  • Biochemistry
  • Bioinformatics
  • Genomics

Background:

  • Proteomic data dissemination is crucial in the post-genomic era.
  • Web-based databases are effective for sharing proteomic information.
  • A specialized resource for dental tissue proteomics is needed.

Purpose of the Study:

  • To establish ToothPrint, a novel proteomic database for dental tissues.
  • To provide functionally relevant data beyond basic protein identification.
  • To create a user-friendly and computationally accessible bioinformatic tool.

Main Methods:

  • Development of a World Wide Web accessible database.
  • Utilizing developing rat enamel as a prototype system.
  • Integration of protein identification maps with functional data (ligand binding, subcellular localization, developmental regulation).

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Main Results:

  • ToothPrint database successfully established and accessible online.
  • The database includes protein identification and diverse functional data for dental tissues.
  • Features enhancing usability and simplifying computational requirements are implemented.

Conclusions:

  • ToothPrint serves as an effective bioinformatic resource for dental biology.
  • The database facilitates the dissemination and integration of proteomic data for mineralizing tissues.
  • It supports advanced investigations in dental research.