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Updated: Aug 1, 2026

A Novel Digital Platform for a Monitored Home-based Cardiac Rehabilitation Program
Published on: April 19, 2019
The Norsjö-Cooperstown healthy heart project: a case study combining data from different studies without the use of
P L Jenkins1, L Weinehall, T A Erb
1The Mary Imogene Bassett Research Institute, Cooperstown, New York 13326-1394, USA. paul.jenkins@bassett.org
Objectives:
This paper aims to develop and describe a method for combining. comparing, and maximizing the statistical power of two longitudinal studies of risk factors for cardiovascular disease that did not have identical data collection methodologies.
Methods:
Subjects from a 1986 cross-sectional study (n = 180) were pair-matched with subjects of corresponding gender and age (+5 years) from a 1990 cross-sectional study. The methodology is described and results are calculated for various measures of cardiovascular risk or risk factors (e.g. cholesterol. Finnish Risk Score).
Results:
Box's test of equality and symmetry of covariance matrices gave chi-square values of 223.8 and 710.0 for two cardiovascular risk factors (cholesterol and cardiac risk score, respectively); these values were highly significant (p=0.0001) For the North Karelia Risk Score, repeated measures ANOVA revealed a borderline significant interaction for treatment by time (p=0.054) and a significant interaction for treatment by time by country (p=0.035). These probabilities compared favorably with a randomized blocks model.
Conclusions:
Creation of a synthetic longitudinal control group resulted in a statistically valid ANOVA model that increased the statistical power of the study.
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