Related Experiment Video
Updated: Sep 11, 2026

An Allele-specific Gene Expression Assay to Test the Functional Basis of Genetic Associations
Published on: November 3, 2010
The neutral theory in the genomic era
1Committee on Genetics, University of Chicago, 1101 East 57th Street, Chicago, Illinois 60637, USA. jcfay@lbl.gov
Abstract:
A number of tests have been developed to detect positive selection at the molecular level. These tests are based on DNA polymorphism within and divergence between species. Applications of these tests have revealed a large collection of genes that have evolved under positive selection and some general insights into adaptive evolution. Recently, these tests have been applied on a genomic scale and have provided estimates of the frequency of adaptive substitutions and a critical test of the neutral theory.
More Related Videos
11:35Screening for Functional Non-coding Genetic Variants Using Electrophoretic Mobility Shift Assay (EMSA) and DNA-affinity Precipitation Assay (DAPA)
Published on: August 21, 2016
08:54In vivo Application of the REMOTE-control System for the Manipulation of Endogenous Gene Expression
Published on: March 29, 2019
Related Concept Videos
Hardy-Weinberg Principle
Chromosomal Theory of Inheritance
Genomics
Genome Size and the Evolution of New Genes
Genome Size and the Evolution of New Genes
Evolution of Microbial Genome