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Eudesmanolides, aromatic derivatives, and other constituents from Carpesium cernuum
1Department of Chemistry, National Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou, People's Republic of China.
Die Pharmazie
|October 31, 2001
Abstract:
A new eudesmanolide 13-hydroxy-4 alpha H-eudesman-5,7(11)-dien-12,8 beta-olide (1) and a new aromatic derivative 3-methyl-8-acetoxy-9,10-diisobutanoyloxy-p-cymene (6), along with ten known compounds were isolated from the roots of Carpesium cernuum L. Their structures were elucidated by spectral methods (IR, EIMS, FAB-MS, 1D and 2D NMR). Compound 2, 3 and compound 10 exhibited moderate antibacterial activity against Bacillus subtilis, Escherichia coli and Staphylococcus aureus.