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Updated: Jul 14, 2026

A Pipeline for 3D Multimodality Image Integration and Computer-assisted Planning in Epilepsy Surgery
Published on: May 20, 2016
Multimodality image-guided epilepsy surgery
M Murphy1, T J O'Brien, K Morris
1Department of Neurosurgery, The Victorian Epilepsy Centre at St Vincent's Hospital, 41 Victoria Pde, Fitzroy, Victoria 3065, Australia. murphyma@svhm.org.au
Abstract:
Co-registration of imaging modalities in the diagnosis of epilepsy is now commonly used in major epilepsy centres. However, the incorporation of these registrations into an image-guided system has only recently been developed. Using techniques of segmentation, surface matching and/or voxel-based matching, we have been able to co-register FLAIR MRI, SPECT, PET, and subdural grids into the 3-D space of the volumetric MRI and use these images on the StealthStation Image-Guided System to resect these foci. This greatly aids the surgeon in performing a more precise tailoring of the cortical resection so as to maximize the excision of the epileptogenic zone while minimizing the impact on eloquent cortex and epileptogenic foci.
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