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Auscultatory features of hypertrophic obstructive cardiomyopathy. A study of 90 patients

R B Tucker, M M Zion, W A Pocock

    South African Medical Journal = Suid-Afrikaanse Tydskrif Vir Geneeskunde
    |February 8, 1975
    PubMed

    Insights

    This study details the heart sounds in hypertrophic obstructive cardiomyopathy (HOCM). Key findings include murmurs and abnormal heart sounds indicating outflow tract obstruction and mitral incompetence in HOCM patients.

    Area of Science:

    • Cardiology
    • Internal Medicine
    • Physiology

    Background:

    • Hypertrophic obstructive cardiomyopathy (HOCM) is a complex cardiac condition.
    • Understanding its auscultatory signs is crucial for diagnosis and management.

    Purpose of the Study:

    • To describe the diverse auscultatory findings in 90 subjects with HOCM.
    • To correlate these findings with the underlying pathophysiology of outflow tract obstruction.

    Main Methods:

    • Clinical auscultation of 90 patients diagnosed with HOCM.
    • Observation of murmurs, clicks, and heart sound variations.
    • Assessment of responses to vaso-active maneuvers.

    Main Results:

    • Late-onset ejection systolic murmurs indicate volume-dependent outflow tract obstruction.
    • Mitral incompetence is associated with late systolic murmur vibrations.
    • Abnormalities in the second heart sound, including reversed splitting, correlate with severe left ventricular outflow obstruction.

    Conclusions:

    • Auscultation reveals key signs of outflow tract obstruction and mitral incompetence in HOCM.
    • Second heart sound patterns offer insights into the severity of left ventricular obstruction.

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