Related Experiment Video
Updated: Aug 10, 2026
08:48
Adapted Resistance Training Improves Strength in Eight Weeks in Individuals with Multiple Sclerosis
Published on: January 29, 2016
Living with Marfan syndrome II. Medication adherence and physical activity modification
1Department of Medicine, Center for Developmental and Health Genetics, Pennsylvania State University, University Park, PA 16802, USA. kfp1@psu.edu
Clinical Genetics
|October 31, 2001
Summary
Adults with Marfan syndrome generally adhere to medication and physical activity guidelines. However, perceptions of necessity and condition impact adherence, highlighting the need for tailored genetic counseling.
Area of Science:
- Cardiology
- Genetics
- Psychology
Background:
- Marfan syndrome is a genetic disorder affecting connective tissue.
- Management involves medication and lifestyle modifications, including physical activity.
- Understanding patient perceptions is crucial for adherence.
Purpose of the Study:
- To investigate perceptions and adherence to medication and physical activity guidelines in adults with Marfan syndrome.
- To identify factors influencing adherence to treatment recommendations.
- To inform genetic counseling strategies for Marfan syndrome patients.
Main Methods:
- Survey of 174 adults with Marfan syndrome.
- Assessed adherence to beta- and Ca2+-channel blockers.
- Evaluated physical activity choices and perceptions of Marfan syndrome.
Main Results:
- Over 80% reported good adherence to prescribed beta- and Ca2+-channel blockers.
- Cardiovascular symptoms and fatigue correlated positively with medication use.
- Physical activity modification was linked to perceiving Marfan syndrome as having negative life consequences.
- Beliefs about medication necessity were associated with regimen duration, type, and perceived controllability.
Conclusions:
- Adults with Marfan syndrome show high adherence but variable perceptions of medication necessity.
- Physical activity modifications reflect perceived condition impact.
- Genetic counseling should address patient beliefs regarding medication and exercise for improved coping and adherence.
More Related Videos
Related Concept Videos
01:27Mitral Stenosis IV: Nursing Management
A comprehensive nursing assessment is essential for patients with valvular heart disease, which involves any dysfunction of the heart valves that could impact blood flow and overall heart function.Subjective Data Collection:Chief Complaint and Present Illness: Start with the patient's primary concerns, focusing on the onset, duration, and progression of cardiac symptoms such as dyspnea, fatigue, chest pain, and palpitations.Past Medical History: Collect detailed information on any previous...
01:25Aortic Regurgitation III: Medical Management
Aortic regurgitation (AR) is when the aortic valve does not close or seal properly, leading to backward blood circulation from the aorta into the left ventricle during diastole. Common causes of AR include rheumatic heart disease, congenital valve defects, and aortic root dilation. Managing AR requires a multifaceted approach to alleviate symptoms, preserve left ventricular function, and address the underlying cause of the regurgitation. Patients with symptomatic AR or significant left...
01:30Heart Failure VII: Nursing Interventions
The first step in nursing management of a patient with heart failure involves thoroughly assessing the patient's medical history.Subjective Data: Obtain the patient's medical history of coronary artery disease, hypertension, myocardial infarction, and symptoms like dyspnea, orthopnea, and paroxysmal nocturnal dyspnea.Objective Data: Conduct a physical examination to identify findings such as jugular vein distention, pulmonary crackles, tachycardia, murmurs, peripheral edema, and vital signs,...
01:29Cardiomyopathy V: Interprofessional Care
Managing cardiomyopathy involves addressing underlying or precipitating causes, treating heart failure with medications, and implementing dietary changes and a balanced exercise and rest regimen.Lifestyle ModificationsCardiomyopathy patients should adopt a low-sodium diet to reduce fluid retention and manage heart failure. A personalized exercise and rest plan helps maintain physical fitness without overstraining the heart. Avoiding alcohol and tobacco is essential to prevent further damage to...
01:29Cardiomyopathy VI: Nursing Management
Assessment: Nursing management of patients with cardiomyopathy begins with a thorough assessment of the patient's history, including a family history of cardiomyopathy or sudden cardiac death, personal history of heart disease, hypertension, diabetes, and any alcohol consumption or drug use.During the physical examination, assess vital signs, look for signs of heart failure (such as edema, jugular venous distention, and cyanosis), auscultate for abnormal heart sounds (like murmurs and gallops),...
01:26Atherosclerosis III: Management
Management of atherosclerosis involves an integrated strategy encompassing pharmacological treatment, surgical interventions, lifestyle changes, and nutrition therapy to address the multifactorial nature of the disease.Pharmacological TherapyA cornerstone of atherosclerosis management is the use of pharmacological agents. Statins, such as atorvastatin, are pivotal in inhibiting HMG-CoA reductase, an enzyme that catalyzes an initial step in cholesterol synthesis in the liver. This reduction in...