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Translocation t(4; 6)(q21; q27) in a case of primary thrombocythaemia in transformation
I Krsnik1, T Ferro, J García Suárez
1Servicio de Hematología, Hospital Universitario Príncipe de Asturias, Alcalá de Henares, Madrid, Spain. ikrsnik@hupa.insalud.es
Clinical and Laboratory Haematology
|October 31, 2001
Abstract:
We report a case of primary thrombocythaemia showing a translocation t(4; 6)(q21; q27) five years after diagnosis. The patient had been treated with hydroxyurea. The clinical picture at the time was consistent with transformation. Karyotypic abnormalities are rare in this disease and are reviewed.