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Updated: Aug 20, 2026

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Creation of Reversible Cholestatic Rat Model
Published on: May 21, 2011
Conditioned taste aversion and c-Fos expression in cholestatic rats
Brain Research
|October 31, 2001
Abstract:
Rats in which a ligation of the bile duct (BDL) was paired with a saccharin taste developed a persistent conditioned taste aversion in both preference and taste reactivity tests. All BDL animals regardless of pairing had increased c-Fos-like immunoreactivity (FLI) in the area postrema and the nucleus of the solitary tract. This FLI may reflect the illness associated with BDL, but there was no evidence of conditioned FLI.

