Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Vitamin K and bone health.

P Weber1

  • 1Vitamins and Fine Chemicals Division, Human Nutrition & Health, F. Hoffmann-La Roche Ltd, CH-4070 Basel, Switzerland. peter.weber@roche.com

Nutrition (Burbank, Los Angeles County, Calif.)
|October 31, 2001
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[The first French fall prevention day for elderly people].

Geriatrie et psychologie neuropsychiatrie du vieillissement·2025
Same author

Antibiotic resistance of urinary pathogens after kidney transplantation: a 10-year single-center survey in Germany.

Infection·2025
Same author

[Perioperative management of obese patients undergoing elective hip and knee arthroplasty].

Orthopadie (Heidelberg, Germany)·2025
Same author

Achievement of Target Gain Larger than Unity in an Inertial Fusion Experiment.

Physical review letters·2024
Same author

Smoking exposure trajectories and pulmonary function in early adulthood in a Brazilian cohort.

Pulmonology·2023
Same author

What makes community-based, multilevel physical activity promotion last? A systematic review with narrative synthesis on factors for sustainable implementation.

Perspectives in public health·2023
Same journal

Different approaches of strength-to-muscle mass ratio: impact on 24-month outcomes in patients with acute coronary syndrome.

Nutrition (Burbank, Los Angeles County, Calif.)·2026
Same journal

From scriptural reference to scientific evidence a critical review of the nutritional composition and functional food potential of foods described in classical Islamic texts.

Nutrition (Burbank, Los Angeles County, Calif.)·2026
Same journal

Integrating BIA-derived body composition parameters with GLIM criteria for survival prediction in patients with solid tumors.

Nutrition (Burbank, Los Angeles County, Calif.)·2026
Same journal

Polyunsaturated fatty acids in the prevention, treatment, and survival of breast cancer.

Nutrition (Burbank, Los Angeles County, Calif.)·2026
Same journal

Unpacking the eating pathways: The mediating roles of emotional eating and problem-solving skills in the relationship between childhood trauma and eating expectancies.

Nutrition (Burbank, Los Angeles County, Calif.)·2026
Same journal

Improving communication about dietary fats: development and validation of the Fats-Related Attitude Scale based on data from Brazil, China, Croatia, Poland, and Spain.

Nutrition (Burbank, Los Angeles County, Calif.)·2026
See all related articles

Vitamin K plays a crucial role in bone health, improving bone mineral density and reducing fracture rates. Emerging research suggests vitamin K, especially when combined with vitamin D, offers significant benefits for skeletal health.

Area of Science:

  • Nutritional Science
  • Bone Metabolism
  • Biochemistry

Background:

  • Vitamin K's established role in blood clotting is now complemented by evidence of its importance in bone health.
  • Epidemiologic and intervention studies consistently highlight vitamin K's positive impact on skeletal integrity.
  • The synergistic effects of vitamins K and D on bone density are increasingly recognized.

Purpose of the Study:

  • To explore the multifaceted roles of vitamin K in human health beyond coagulation.
  • To evaluate the efficacy of vitamin K supplementation in improving bone mineral density and reducing fracture risk.
  • To investigate the mechanisms through which vitamin K influences bone metabolism and calcium balance.

Main Methods:

  • Analysis of human epidemiologic and intervention studies.

Related Experiment Videos

  • Review of studies employing vitamin K2 at high doses and vitamin K1 at lower doses, often with vitamin D coadministration.
  • Examination of proposed biochemical pathways, including osteocalcin gamma-carboxylation and calcium balance modulation.

    • Main Results:

    • Intervention studies show vitamin K can increase bone mineral density and decrease fracture rates in osteoporotic individuals.
    • Evidence suggests a synergistic effect between vitamin K and vitamin D on bone density.
    • Emerging data indicate vitamin K1 may benefit bone health at lower doses, particularly with vitamin D.

    Conclusions:

    • Vitamin K is essential for maintaining bone health, with demonstrated benefits for bone mineral density and fracture reduction.
    • The synergistic action of vitamins K and D presents a promising strategy for enhancing bone health.
    • Updated dietary reference intakes reflect the growing understanding of vitamin K's critical role in bone metabolism.