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Unilateral corneal lattice dystrophy.

M S Sridhar1, P R Laibson, R C Eagle

  • 1Cornea Service, Wills Eye Hospital, Philadelphia, Pennsylvania 19107, USA.

Cornea
|October 31, 2001
PubMed
Summary
This summary is machine-generated.

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Lattice corneal dystrophy can appear unilateral but may affect the other eye years later, potentially causing vision loss. Early diagnosis and patient education are crucial for managing this rare condition.

Area of Science:

  • Ophthalmology
  • Genetics

Background:

  • Lattice corneal dystrophy (LCD) is a rare, inherited eye disease.
  • Type I classic LCD typically presents with bilateral corneal opacities.

Observation:

  • This study details three cases of LCD initially presenting as unilateral.
  • Patients exhibited lattice lesions in one eye and a healthy fellow eye.
  • Two patients required penetrating keratoplasty due to vision impairment.

Findings:

  • Histopathology confirmed amyloid deposits consistent with LCD in one patient.
  • The fellow eye of one patient developed lattice lesions 13 years after initial examination.
  • This suggests LCD may have a delayed onset in the contralateral eye.

Implications:

Related Experiment Videos

  • LCD, even when seemingly unilateral, can lead to significant vision loss.
  • The possibility of delayed contralateral eye involvement must be communicated to patients.
  • This highlights the importance of long-term monitoring for apparently unilateral LCD.