Related Experiment Video
Updated: Aug 4, 2026

Live-cell Video Microscopy of Fungal Pathogen Phagocytosis
Published on: January 9, 2013
Potocytosis. Robert Feulgen Lecture
1Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, Texas 75235-9039, USA.
Abstract:
Potocytosis represents a mechanism by which small and large molecules as well as macromolecular complexes are sequestered and transported by caveolae. Caveolae are flask-shaped plasma membrane specializations characterized by a filamentous coat consisting of caveolins that decorates the inside surface of each caveola membrane. They have endocytotic functions that differ from the clathrin-coated pit pathway. Ligands bound to receptors that are internalized by caveolae can be delivered to four different locations in the cell bypassing the lysosome and at least four different caveolae membrane traffic patterns during potocytosis can be distinguished. Hence, cells have two endocytic machines and each is designed to accomplish different tasks. This review provides a brief summary of the discovery of caveolae and of potocytosis, and focuses on recent discoveries of the unique endocytic capabilities of caveolae in a variety of different cells.
Related Concept Videos
Pinocytosis
Phagocytosis
Pinocytosis
Pinocytosis ("cellular drinking") is one of three main types of endocytosis. In...
COP Coated Vesicles

