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Related Experiment Videos

[Transeptal steroids in necrotizing scleritis].

M Sainz De La Maza Serra1, J Folch Ramos

  • 1Servicio de Oftalmología, Unidad de Inmunología Ocular y Uveítis, Hospital Clínico y Provincial de Barcelona, España.

Archivos De La Sociedad Espanola De Oftalmologia
|October 31, 2001
PubMed
Summary

Transeptal corticosteroid injections effectively managed active inflammation in necrotizing scleritis when used alongside systemic immunosuppressors, with minimal side effects observed in patients.

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[Characteristics of scleritis in patients older than 60 years].

Archivos de la Sociedad Espanola de Oftalmologia·2001
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Area of Science:

  • Ophthalmology
  • Rheumatology
  • Immunology

Context:

  • Necrotizing scleritis is a severe inflammatory eye condition.
  • Systemic immunosuppressors are the primary treatment.
  • Periods of active inflammation pose a treatment challenge.

Purpose:

  • To evaluate the efficacy of transeptal corticosteroid injections as an adjunct therapy for necrotizing scleritis.
  • To assess the safety and effectiveness of this combined treatment approach.

Summary:

  • Eleven patients with necrotizing scleritis received transeptal corticosteroid injections in addition to their systemic immunosuppressors during active inflammation flares.
  • This combined treatment successfully halted active inflammation in 10 out of 11 patients.
  • No increase in immunosuppressor dosage or change in medication was required, and no significant adverse events like scleral perforation or thinning were noted.

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Impact:

  • Transeptal corticosteroid injections offer a safe and effective supplementary treatment option for necrotizing scleritis.
  • This approach can help control inflammation without escalating systemic immunosuppression.
  • It may reduce the risk of severe ocular complications associated with uncontrolled inflammation.