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Updated: Aug 9, 2026
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Image-Guided Resection of Glioblastoma and Intracranial Implantation of Therapeutic Stem Cell-seeded Scaffolds
Published on: July 16, 2018
Biopsy versus resection for malignant glioma
1c/o Edinburgh Centre of Neuro-Oncology, Western General Hospital, Crewe Road, Edinburgh, Scotland, UK, EH4 2XU. sarahmetcalfe10@hotmail.com
The Cochrane Database of Systematic Reviews
|November 1, 2001
Summary
This review found no studies comparing malignant glioma resection to biopsy. Further research is needed to determine the optimal surgical approach for patients with brain tumors.
Area of Science:
- Neurosurgery
- Oncology
- Clinical Trials
Background:
- Patients with supratentorial brain tumors face a choice between biopsy and resection.
- Surgical opinions are divided on the risks and benefits of each procedure.
Purpose of the Study:
- To estimate the clinical effectiveness of radical surgical resection versus simple biopsy in malignant glioma patients.
Main Methods:
- Comprehensive electronic database searches were conducted.
- Hand searching of references and relevant journals was performed.
- No randomized or clinical controlled trials met the inclusion criteria.
Main Results:
- Extensive searches yielded no studies comparing biopsy to resection for malignant glioma.
- No data could be synthesized due to the lack of qualifying studies.
Conclusions:
- No qualifying studies were identified for this important clinical and economic issue.
- A randomized controlled trial is crucial to guide surgical management decisions.
