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Related Experiment Videos

Caffeine for asthma.

A I Bara1, E A Barley

  • 1Department of Public Health Sciences, St George's Hospital Medical School, Cranmer Terrace, Tooting, London, UK, SW17 ORE. airways@sghms.ac.uk

The Cochrane Database of Systematic Reviews
|November 1, 2001
PubMed
Summary
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Caffeine consumption may offer a modest, short-term improvement in lung function for individuals with asthma. Patients should avoid caffeine for at least four hours before pulmonary function tests.

Area of Science:

  • Pharmacology
  • Respiratory Medicine
  • Clinical Trials

Background:

  • Caffeine, a stimulant, shares chemical similarities with theophylline, a medication used for asthma treatment.
  • Previous studies suggest caffeine may benefit asthma patients by acting as a weak bronchodilator and reducing respiratory muscle fatigue.
  • This review systematically examines existing evidence on caffeine's effects in asthma.

Purpose of the Study:

  • To assess the impact of caffeine on lung function in adults with asthma.
  • To determine if caffeine consumption influences the accuracy of pulmonary function testing.

Main Methods:

  • Systematic review of randomized controlled trials comparing oral caffeine to placebo in adult asthma patients.
  • Searched the Cochrane Airways Group trials register and reference lists; contacted study authors.

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  • Independent quality assessment and data extraction by two reviewers.

    • Main Results:

    • Six high-quality, cross-over trials involving 55 participants were included.
    • Caffeine demonstrated a modest improvement in lung function for up to two hours post-consumption.
    • Forced expiratory volume in one second (FEV1) and mid-expiratory flow rates showed significant improvements.

    Conclusions:

    • Caffeine provides a moderate, temporary enhancement of airway function in asthma patients, lasting up to four hours.
    • Recommendations suggest avoiding caffeine intake for a minimum of four hours before undergoing lung function tests to ensure accurate results.