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High Resolution 3D Imaging of Ex-Vivo Biological Samples by Micro CT
Published on: June 21, 2011
Image quality and dose comparison among screen-film, computed, and CT scanned projection radiography: applications to
C H McCollough1, M R Bruesewitz, T J Vrtiska
1Department of Radiology, E2-A, Mayo Clinic and Foundation, 200 First St SW, Rochester, MN 55905, USA. mccollough.cynthia@mayo.edu
Purpose:
To evaluate image quality and dose for abdominal imaging techniques that could be used as part of a computed tomographic (CT) urographic examination: screen-film (S-F) radiography or computed radiography (CR), performed with moving and stationary grids, and CT scanned projection radiography (CT SPR).
Materials And Methods:
An image quality phantom underwent imaging with moving and stationary grids with both a clinical S-F combination and CR plate. CT SPR was performed with six CT scanners at various milliampere second and kilovolt peak settings. Entrance skin exposure (ESE); spatial, contrast, and temporal resolutions; geometric accuracy; and artifacts were assessed.
Results:
S-F or CR images, with either grid, provided image quality equivalent to that with the clinical standard, S-F with a moving grid. ESE values for both S-F and CR were 435 mR (112.2 microC/kg [1 mR = 0.258 microC/kg]) with a moving grid and 226 mR (58.3 microC/kg) with a stationary grid. All CT SPR images provided inferior spatial resolution compared with S-F or CR images. High-contrast objects generated substantial artifacts on CT SPR images. Compared with S-F, CR and CT SPR provided improved resolution of small low-contrast objects. The contrast between iodine and soft-tissue-mimicking structures on CT SPR images acquired at 80 kVp was twice that at 120 kVp. CT SPR images with acceptable noise levels required a midline ESE value of approximately 300 mR (77.4 microC/kg) at 80 kVp.
Conclusion:
S-F and CR provided better spatial resolution than did CT SPR. However, CT SPR provided improved low-contrast resolution compared with S-F, at exposures comparable to those used for S-F or CR.
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