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[Pseudomigraine with pleocytosis].

B Spelsberg1, C Willert, J Machetanz

  • 1Klinik und Poliklinik für Neurologie, Klinik und Poliklinik für Psychiatrie und Psychotherapie, Ernst-Moritz-Arndt-Universität Greifswald im Klinikum Stralsund, Rostocker Chaussee 70, 18437 Stralsund. spitzer@mail.uni-greifswald.de

Der Nervenarzt
|November 2, 2001
PubMed
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Two young men experienced brief neurological episodes with fever and headache. Doctors diagnosed pseudomigraine with pleocytosis, a rare condition.

Area of Science:

  • Neurology
  • Neuroscience

Background:

  • The abstract discusses a rare neurological condition.
  • It highlights the importance of accurate diagnosis in neurological disorders.

Observation:

  • Two male patients, aged 32 and 34, presented with acute headache, fever, and transient focal neurological deficits.
  • Cerebrospinal fluid (CSF) analysis revealed lymphocytic pleocytosis without an identifiable infectious agent.
  • Electroencephalogram (EEG) showed focal slowing during attacks, normalizing afterward. Standard neuroimaging and blood tests were unremarkable.

Findings:

  • The patients were diagnosed with pseudomigraine with pleocytosis (PMP), a recently described neurological entity.
  • PMP is characterized by recurrent, short-lived attacks of headache, nausea, vomiting, focal neurological deficits, and CSF lymphocytic pleocytosis.

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  • The condition resolved spontaneously within hours in both reported cases.

    • Implications:

    • Accurate differentiation of PMP from vascular disorders is crucial.
    • Angiography should be approached with caution in suspected PMP cases due to potential complications.
    • This case report contributes to the understanding of PMP and its clinical presentation.