[The prognostic value of poly-organic insufficiency in patients with acute pancreatitis]
Related Experiment Video
Updated: Oct 3, 2026

Preparing a Mice Model of Severe Acute Pancreatitis via a Combination of Caerulein and Lipopolysaccharide Intraperitoneal Injection
Published on: May 10, 2024
Abstract:
The results of surgical treatment of 148 patients aged from 18 to 83 years old suffering from acute pancreatitis (AP) were analyzed. Acute biliary pancreatitis (ABP) was determined in 49.3% of patients. The use of biochemical, ultrasound, endoscopic and laparoscopic methods of diagnostics permitted to determine the pathogenesis of AP and initial manifestation of polyorganic insufficiency syndrome (POIS). In 58.8% of patients mild intoxication syndrome was observed, in 41.2% it was considered severe. 56.1% of patients underwent surgical treatment that included laparocentesis, laparoscopy, and toxic exudate removement, drainage of abdominal cavity. In patients with ABP laparoscopic cholecystectomy and the drainage of common bile duct was performed. Total mortality was 5.4%. The wide introduction of endovideosurgical technologies permits to perform several actions in order to treat AP, to prevent POIS and pyo-necrotic complications and to achieve the decrease of mortality.
Related Concept Videos
Acute Pancreatitis II: Clinical Manifestations and Management
Chronic Pancreatitis I: Introduction
Chronic Pancreatitis I: Introduction
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
Acute Pancreatitis II: Pathophysiology
Chronic Pancreatitis II: Pathophysiology
Acute Pancreatitis I: Introduction
