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Published on: February 16, 2011
Chronic active myocarditis following acute Bartonella henselae infection (cat scratch disease)
G R Meininger1, T Nadasdy, R H Hruban
1Department of Medicine, Johns Hopkins Hospital, Baltimore, Maryland, USA.
Insights
Bartonella henselae infection can cause chronic active myocarditis, leading to severe heart failure. This finding suggests Bartonella should be recognized as a cause of myocarditis.
Area of Science:
- Cardiology
- Infectious Diseases
- Pathology
Background:
- Myocarditis is inflammation of the heart muscle.
- Bartonella henselae is a bacterium known to cause cat scratch disease.
- A link between Bartonella infection and myocarditis has not been previously established.
Observation:
- A case study of a young, healthy male patient is presented.
- The patient developed chronic active myocarditis following Bartonella henselae infection.
- The condition progressed to severe heart failure.
Findings:
- Bartonella henselae infection was identified as the cause of chronic active myocarditis in this patient.
- The patient required an orthotopic heart transplant due to the severity of heart failure.
- This case demonstrates a novel association between Bartonella henselae and myocardial inflammation.
Implications:
- Bartonella henselae should be considered in the differential diagnosis of infectious agents causing chronic active myocarditis.
- Further research is warranted to understand the prevalence and mechanisms of Bartonella-associated myocarditis.
- This finding may impact clinical guidelines for diagnosing and managing myocarditis, particularly in cases with unclear etiology.
Abstract:
An association between Bartonella infection and myocardial inflammation has not been previously reported. We document a case of a healthy young man who developed chronic active myocarditis after infection with Bartonella henselae (cat scratch disease). He progressed to severe heart failure and underwent orthotopic heart transplantation. Bartonella henselae, therefore, should be included among the list of infectious agents associated with chronic active myocarditis.
Related Concept Videos
Myocarditis I: Introduction
Myocarditis II: Clinical Features and Diagnostic Tests
Myocarditis III: Medical Management
Rheumatic Heart Disease I: Introduction
Acute Coronary Syndrome I: Introduction
Cardiomyopathy III: Hypertrophic Cardiomyopathy

