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Antagonistic effect of cyproheptadine on neuroleptic-induced catalepsy
Pharmacology, Biochemistry, and Behavior
|January 1, 1975
Abstract:
The influence of cyproheptadine on the neuroleptic-catalepsy in rats was studied. Cyproheptadine antagonized dose-dependently the catalepsy induced by spiroperidol, pimozide, fluphenazine and reserpine. The anticataleptic effect of two antiparkinsonian drugs, L-DOPA or amantadine was potentiated by cyproheptadine.