Statistical analysis of the DNA sequence of human chromosome 22

¹Department of Theoretical Biophysics, Humboldt University Berlin, Invalidenstrasse 42, D-10115, Berlin, Germany.

Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics

|November 3, 2001

Abstract:

We study statistical patterns in the DNA sequence of human chromosome 22, the first completely sequenced human chromosome. We find that (i). the 33.4 x 10(6) nucleotide long human chromosome exhibits long-range power-law correlations over more than four orders of magnitude, (ii). the entropies H(n) of the frequency distribution of oligonucleotides of length n (n-mers) grow sublinearly with increasing n, indicating the presence of higher-order correlations for all of the studied lengths 1

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Statistical analysis of the DNA sequence of human chromosome 22

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Abstract:

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