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Updated: Oct 3, 2026

Generation of Genetically Modified Organotypic Skin Cultures Using Devitalized Human Dermis
Published on: December 14, 2015
The use of an acellular dermal skin graft to gain keratinized tissue
1Department of Periodontics, University of Mississippi School of Dentistry, Jackson, Mississippi, USA.
Abstract:
For decades, free gingival grafting has been a predictable and widely used procedure to gain keratinized tissue around teeth with mucogingival problems. Recently, a biocompatible, acellular, connective tissue material (AlloDerm) made from human dermis has been introduced as an alternative to the conventional use of autogenous tissue. This material eliminates the need for donor sites, and it minimizes postoperative discomfort and complications. It also integrates well to the recipient site, and it provides an excellent color match with the surrounding tissues, making it esthetically pleasing.

