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Malignant lymphoma in primary Sjogren's syndrome
M Voulgarelis1, H M Moutsopoulos
1Department of Pathophysiology, Medical School, National University of Athens, Athens, Greece.
The Israel Medical Association Journal : IMAJ
|November 6, 2001
Abstract:
Sjogren's syndrome is a chronic inflammatory process involving primarily the exocrine glands. Its association with lymphoma is well documented. A low grade marginal-zone lymphoma related to mucosa-associated lymphoid tissue is the commonest lymphoid neoplasia in Sjogren's syndrome. We review the literature and comment on the molecular, clinical, histopathologic and therapeutic aspects of these tumors in Sjogren's syndrome.