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Irritable bowel syndrome: new approaches to its pharmacological management
1Intestinal Disease Research Program, Division of Gastroenterology, McMaster University Medical Centre, 1200 Main Street West, Hamilton, Ontario L8N 3Z5, Canada. tougasg@mcmaster.ca
Abstract:
The present paper examines approaches to drug therapy for irritable bowel syndrome (IBS). Because IBS is associated with multiple symptoms, no single therapy is effective in all patients. However, issues such as affective and emotional factors also need to be addressed when treating patients with IBS. This paper emphasizes the importance of identifying new pharmaceutical approaches to treat a multitude of symptoms and obtaining a better understanding of the underlying mechanisms of IBS.