Concepts for the prophylaxis of infective endocarditis in dentistry

Oral commensal microorganisms are commonly associated with the pathogenesis of infective endocarditis. Despite modern antimicrobial and surgical treatment, infective endocarditis continues to cause substantial morbidity and mortality. Although dentistry is no longer considered a major risk factor for infective endocarditis, it is current standard for practice that dental procedures likely to produce significant bacteraemia in patients who are susceptible to this disease be prophylactically covered with an antimicrobial agent. The concepts of antimicrobial prophylaxis prior to invasive dental procedures are outlined in this review, with particular reference to the latest recommendations of the Australian Dental Association.