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Updated: Jul 18, 2026

Evaluating the Effectiveness of Cancer Drug Sensitization In Vitro and In Vivo
Published on: February 6, 2015
Assessment of human cancer risk: challenges for alternative approaches
1The University of Michigan, Ann Arbor 48109-0626, USA.
Abstract:
The ILSI/HESI Workshop on Alternatives to Carcinogenicity Testing aims to develop and apply new methods for assessment of potential carcinogenic risk to humans from various chemicals. The Workshop represents a major cooperative scientific effort. The long-term goals should be to greatly enhance the efficiency and reliability of such testing and to supplant, not just supplement, lifetime rodent bioassays. There are now well-established frameworks for risk assessment and risk management, putting risks into public health context and engaging stakeholders. The Lave-Omenn value-of-information model provides a useful way to assess the social costs and benefits of different strategies for testing large numbers of chemicals.
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