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Adesmia aegiceras: antimicrobial activity and chemical study
A M Agnese1, C Pérez, J L Cabrera
1Instituto Multidisciplinario de Biología Vegetal (IMBIV-CONICET), Departamento de Farmacia, Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, Argentina.
Abstract:
The antimicrobial activity of the ethanolic extract of Adesmia aegiceras was studied by the agar-well diffusion method. Antibacterial activity against Micrococcus luteus and eight pathogenic bacterial strains as well as antifungal activity against Candida albicans, was detected. Bacterial and fungal strains exhibited similar concentration-response curves (EC50 and Rmax values) and similar MIC. The MBC/MIC was about 8. These data would indicate the potential usefulness of the A. aegiceras extract as a microbiostatic, antiseptic or disinfectant agent. Furthermore, chemical study of the bioactive alcoholic extract was performed, which revealed quercetin, isorhamnetin-3-rutinoside, isovitexin, pinitol and chlorogenic acid as its main components.