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Updated: Oct 2, 2026

A Method to Study the C924T Polymorphism of the Thromboxane A2 Receptor Gene
Published on: April 1, 2019
Gene Polymorphisms and Outcome After Coronary Angioplasty
Christophe Bauters1, Nicolas Lamblin, Philippe Amouyel
1Service de Cardiologie C, Hôpital Cardiologique, Blvd du Professeur J Leclercq, 59037 Lille Cedex, France. cbauters@chru-lille.fr
Abstract:
This paper discusses the role of genetic factors as predictors of acute closure and restenosis after coronary angioplasty. Two examples are discussed: 1) The phospholipase A(2) (PlA(2)) polymorphism of the platelet glycoprotein IIIa gene, which is associated with different responses of platelets to various agonists, may be a genetic risk factor for coronary thrombosis after stent implantation. 2) The I/D polymorphism of the angiotensin-converting enzyme gene, which is associated with different plasma concentrations of the enzyme, may be a genetic risk factor for restenosis after coronary stenting.
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