Autoimmune type 1 diabetes: resolved and unresolved issues

Determination of secretory granule maturation times in pancreatic islet β-cells by serial block-face electron microscopy.

Journal of structural biology·2020

Combining quantitative 2D and 3D image analysis in the serial block face SEM: application to secretory organelles of pancreatic islet cells.

Journal of microscopy·2015

Quantitative analysis of mouse pancreatic islet architecture by serial block-face SEM.

Journal of structural biology·2014

The dense core vesicle protein IA-2, but not IA-2β, is required for active avoidance learning.

Neuroscience·2014

Co-regulation of intragenic microRNA miR-153 and its host gene Ia-2 β: identification of miR-153 target genes with functions related to IA-2β in pancreas and brain.

Diabetologia·2013

Deletion of Ia-2 and/or Ia-2β in mice decreases insulin secretion by reducing the number of dense core vesicles.

Diabetologia·2011

Cholesterol-responsive NFE2L1-INSIG1 interaction controls VLDL secretion and metabolic dysfunction-associated steatohepatitis pathogenesis in mice.

The Journal of clinical investigation·2026

The splice of life: an isoform-centric view of disease, technology, and therapeutics.

The Journal of clinical investigation·2026

Histone lysine methyltransferases KMT2C and KMT2D join the all-star tumor suppressor team in gastrointestinal cancer.

The Journal of clinical investigation·2026

Targeting hepatic cholesterol sensing to tackle metabolic dysfunction-associated steatohepatitis.

The Journal of clinical investigation·2026

Gut microbe-derived short-chain fatty acids regulate alphavirus arthritis and macrophage activation in mice.

The Journal of clinical investigation·2026

Sterol biosynthesis, brain development, and disease.

The Journal of clinical investigation·2026

Dabrafenib-Induced Cutaneous Eruptions in a Patient With Langerhans Cell Histiocytosis.

Case reports in dermatological medicine·2026

Type 1 diabetes mellitus induced by sintilimab: a case report and related case literature analysis.

Frontiers in endocrinology·2026

Lipocalin-2 Emerges as a Core Pathogenic Mediator and Biomarker in Autosomal Dominant Tubulointerstitial Kidney Disease-UMOD via Transcriptomic Profiling.

Kidney diseases (Basel, Switzerland)·2026

Diffuse Large B-cell Lymphoma Initially Managed As Secondary Immune Thrombocytopenia: A Case Report.

Cureus·2026

Adverse pregnancy outcome associations among women prior to a diagnosis of systemic lupus erythematosus.

Frontiers in lupus·2026

Targeting TKT-associated immunometabolic remodeling attenuates experimental lupus nephritis and NET-related inflammation.

Frontiers in cell and developmental biology·2026

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Autoimmune type 1 diabetes: resolved and unresolved issues

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Determination of secretory granule maturation times in pancreatic islet β-cells by serial block-face electron microscopy.

Combining quantitative 2D and 3D image analysis in the serial block face SEM: application to secretory organelles of pancreatic islet cells.

Quantitative analysis of mouse pancreatic islet architecture by serial block-face SEM.

The dense core vesicle protein IA-2, but not IA-2β, is required for active avoidance learning.

Co-regulation of intragenic microRNA miR-153 and its host gene Ia-2 β: identification of miR-153 target genes with functions related to IA-2β in pancreas and brain.

Deletion of Ia-2 and/or Ia-2β in mice decreases insulin secretion by reducing the number of dense core vesicles.

Cholesterol-responsive NFE2L1-INSIG1 interaction controls VLDL secretion and metabolic dysfunction-associated steatohepatitis pathogenesis in mice.

The splice of life: an isoform-centric view of disease, technology, and therapeutics.

Histone lysine methyltransferases KMT2C and KMT2D join the all-star tumor suppressor team in gastrointestinal cancer.

Targeting hepatic cholesterol sensing to tackle metabolic dysfunction-associated steatohepatitis.

Gut microbe-derived short-chain fatty acids regulate alphavirus arthritis and macrophage activation in mice.

Sterol biosynthesis, brain development, and disease.

Dabrafenib-Induced Cutaneous Eruptions in a Patient With Langerhans Cell Histiocytosis.

Type 1 diabetes mellitus induced by sintilimab: a case report and related case literature analysis.

Lipocalin-2 Emerges as a Core Pathogenic Mediator and Biomarker in Autosomal Dominant Tubulointerstitial Kidney Disease-UMOD via Transcriptomic Profiling.

Diffuse Large B-cell Lymphoma Initially Managed As Secondary Immune Thrombocytopenia: A Case Report.

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Autoimmune type 1 diabetes: resolved and unresolved issues

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