Photoactivated dentin bonding with N-phenyliminodiacetic acid

Area of Science:

• Biomaterials Science
• Dental Materials
• Polymer Chemistry

Background:

• Optimizing adhesive resin and polymerization initiator chemistry is crucial for effective dentin bonding in dental restorations.
• N-phenyliminodiacetic acid (PIDAA) functions as a self-etching primer with potential initiator and co-initiator properties.

Purpose of the Study:

• To correlate adhesive resin and polymerization initiator chemistry with bonding performance on PIDAA-treated dentin.
• To test the hypotheses that adhesive resin composition and polymerization initiator type critically influence composite bonding to dentin.

Main Methods:

• A 3x2 full factorial design evaluated three bonding resins (non-carboxylic, carboxylic acid monomer (PMDM), and combination) with two initiator systems (PIDAA self-cure and PIDAA/camphorquinone dual-cure).
• Composite-to-dentin specimens were prepared using a two-step protocol involving PIDAA treatment followed by resin application and light irradiation.
• Shear bond strength was measured after storage in distilled water, with statistical analysis using two-way ANOVA and Duncan's Multiple Range test.

Main Results:

• Camphorquinone significantly enhanced mean shear bond strengths across all tested adhesive systems (p < 0.0001).
• Moderate bond strengths were achieved with a non-carboxylic resin and camphorquinone on PIDAA-treated dentin.
• The combination of PMDM and camphorquinone yielded the highest mean shear bond strength (p < 0.05).

Conclusions:

• Formulations incorporating PIDAA, PMDM, and camphorquinone are more effective dental bonding systems compared to those lacking these components.
• PIDAA demonstrates positive interactions with both carboxylic acid monomers (PMDM) and the photooxidant camphorquinone, enhancing bonding efficacy.