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Related Concept Videos

Vision01:24

Vision

Vision is the result of light being detected and transduced into neural signals by the retina of the eye. This information is then further analyzed and interpreted by the brain. First, light enters the front of the eye and is focused by the cornea and lens onto the retina—a thin sheet of neural tissue lining the back of the eye. Because of refraction through the convex lens of the eye, images are projected onto the retina upside-down and reversed.
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Related Experiment Video

Updated: Jul 17, 2026

Investigating the Deployment of Visual Attention Before Accurate and Averaging Saccades via Eye Tracking and Assessment of Visual Sensitivity
06:46

Investigating the Deployment of Visual Attention Before Accurate and Averaging Saccades via Eye Tracking and Assessment of Visual Sensitivity

Published on: March 18, 2019

Target selection for saccadic eye movements: direction-selective visual responses in the superior colliculus.

G D Horwitz1, W T Newsome

  • 1Howard Hughes Medical Institute and Department of Neurobiology, Stanford University School of Medicine, Stanford, California 94305, USA.

Journal of Neurophysiology
|November 8, 2001
PubMed
Summary

Superior colliculus (SC) prelude neurons link visual cues to saccade target selection. A subset of these neurons predicts perceptual reports seconds before eye movements, showing direction selectivity.

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Area of Science:

  • Neuroscience
  • Systems Neuroscience
  • Oculomotor Systems

Background:

  • The superior colliculus (SC) is crucial for sensorimotor transformations.
  • Understanding how the SC integrates visual information for saccade target selection is key.

Purpose of the Study:

  • Investigate the role of SC prelude neurons in saccade target selection.
  • Determine if SC neurons link visual stimulus properties to choice-predicting activity.

Main Methods:

  • Used a direction-discrimination task in rhesus monkeys.
  • Recorded prelude neuron activity in the intermediate and deep SC layers.
  • Analyzed direction-selective responses to visual motion stimuli.

Main Results:

  • ~30% of SC prelude neurons showed choice-predicting activity.
  • Half of these neurons exhibited direction-selective responses to motion stimuli.
  • Directional preferences aligned with task demands and neuron movement fields.

Conclusions:

  • A subpopulation of SC prelude neurons links stimulus cues to saccade target selection.
  • These neurons play a role in integrating sensory evidence for perceptual decisions.
  • Findings highlight the SC's involvement in higher-level aspects of oculomotor control.