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Late-onset complications of percutaneous endoscopic gastrostomy in children

D Ségal1, L Michaud, D Guimber

  • 1Division of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, Lille Faculty of Medicine and Children's Hospital, Lille, France.

Journal of Pediatric Gastroenterology and Nutrition
|November 8, 2001
PubMed

Insights

Percutaneous endoscopic gastrostomy (PEG) in children leads to significant late complications, primarily within two years post-insertion. This study found no identifiable clinical risk factors for these complications, highlighting the need for continued monitoring.

Area of Science:

  • Pediatric Gastroenterology
  • Surgical Complications
  • Medical Device Safety

Background:

  • Percutaneous endoscopic gastrostomy (PEG) is a common procedure for enteral nutrition in pediatric patients.
  • While generally safe, late-onset complications can impact patient outcomes and require careful management.
  • Understanding the incidence and nature of these complications is crucial for improving patient care.

Purpose of the Study:

  • To document the frequency and types of late-onset complications following PEG insertion in children.
  • To investigate potential clinical risk factors associated with the development of these complications.
  • To provide insights into the long-term safety profile of PEG in a pediatric population.

Main Methods:

  • A retrospective analysis of 110 pediatric patients who underwent PEG insertion using the pull technique.
  • Follow-up ranged from 1 to 8 years, recording complications occurring more than 6 days post-insertion (excluding tube obstruction/dislodgement).
  • Statistical tests (Wilcoxon, chi-square) were employed to identify potential risk factors by comparing patient characteristics and device materials.

Main Results:

  • The overall rate of late-onset complications was 44%, with 75% occurring within the first two years.
  • Intragastric buried or extruded gastrostomy was the most frequent complication (n=24).
  • No specific clinical risk factors were identified, although one type of button device was associated with higher rates of buried gastrostomy compared to tubes.

Conclusions:

  • PEG insertion in children is associated with considerable late morbidity, predominantly within the initial two years.
  • Despite the observed complications, this study could not identify any specific clinical risk factors.
  • Further research may be needed to elucidate potential contributing factors and optimize PEG safety in pediatric patients.
Abstract

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