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Published on: July 5, 2021
Iterative atrial tachycardia originating from the coronary sinus musculature
M Tritto1, M Zardini, R De Ponti
1Cardiology Department Mater Domini, Castellanza, Varese, Italy. m.tritto@libero.it
Insights
Iterative atrial tachycardia can cause dilated cardiomyopathy. Radiofrequency ablation targeting the coronary sinus muscular sleeves successfully treated the tachycardia and reversed the cardiomyopathy.
Area of Science:
- Cardiology
- Electrophysiology
- Cardiac Imaging
Background:
- Iterative atrial tachycardia can lead to heart muscle dysfunction.
- Dilated cardiomyopathy is a serious condition affecting heart pumping ability.
Observation:
- A patient presented with tachycardia causing dilated cardiomyopathy.
- Electrophysiologic study revealed irregular tachycardia with atrial activation changes.
- Mapping identified earliest activation near the mitral annulus, but coronary sinus recordings were key.
Findings:
- Radiofrequency ablation in the coronary sinus region eliminated the tachycardia.
- No vessel damage occurred post-ablation.
- The patient recovered fully, with improved left ventricular function.
Implications:
- Muscular sleeves surrounding the coronary sinus may cause tachycardia.
- Tachycardia-induced cardiomyopathy is reversible with successful ablation.
- This case highlights a potential mechanism and treatment for this condition.
Abstract:
A case of iterative atrial tachycardia leading to dilated cardiomyopathy is reported. During electrophysiologic study, the tachycardia showed a markedly irregular cycle length associated with changes in atrial activation breakthrough as demonstrated by coronary sinus (CS) recordings and frequently degenerated into self-terminating atrial fibrillation. Left atrial transseptal mapping demonstrated the earliest endocardial atrial activation close to the posterolateral mitral annulus, but this was invariably later than that recorded within the CS, where low-energy radiofrequency applications eliminated the tachycardia. No acute vessel damage was observed at postablation CS angiography. In accordance with previously published experimental data, we hypothesized that the muscular sleeves surrounding the CS might be involved in the genesis of this tachycardia. During 6-month follow-up, the patient remained asymptomatic without tachycardia recurrences and with complete recovery of left ventricular function, confirming the reversible nature of the tachycardia-induced cardiomyopathy.
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