Related Experiment Video
Updated: Aug 10, 2026

Passive Administration of Monoclonal Antibodies Against H. capsulatum and Others Fungal Pathogens
Published on: February 14, 2011
Use of immunotherapy in previously treated patients with allergic fungal sinusitis
B A Bassichis1, B F Marple, R L Mabry
1Department of Otolaryngology, University of Texas Southwestern Medical Center, Dallas 75390, USA.
Objective:
Sixty patients with a diagnosis of allergic fungal sinusitis were studied. The objective was to show whether, after initial surgical removal of allergic mucin and polyps, immunotherapy decreases re-operation rates and office visits that require medical intervention.
Study Design And Setting:
Sixty patients with adequate follow-up for at least 1 year were evaluated: 24 patients who did not receive immunotherapy and 36 patients whose treatment included postoperative immunotherapy.
Results:
The re-operation rates were 33.0% in those not receiving immunotherapy versus 11.1% in the treated group. Furthermore, the total number of postoperative office visits that required medical therapy decreased from 4.79 per patient to 3.17 with the addition of immunotherapy.
Conclusion/Significance:
These results indicate that immunotherapy is a beneficial part of the overall treatment regimen for allergic fungal sinusitis.
Related Concept Videos
Tumor Immunotherapy
Cryptococcal Meningitis

