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Updated: Jul 30, 2026
08:51
A New Murine Model of Endovascular Aortic Aneurysm Repair
Published on: July 7, 2013
Infected aortic aneurysms: aggressive presentation, complicated early outcome, but durable results.
G S Oderich1, J M Panneton, T C Bower
1Division of Vascular Surgery, Mayo Clinic and Mayo Foundation, Rochester, MN 55905, USA.
Journal of Vascular Surgery
|November 9, 2001
Summary
Infected aortic aneurysms present aggressively but have favorable long-term outcomes with in situ grafting. Key factors for poor prognosis include extensive infection and specific patient characteristics.
Area of Science:
- Vascular Surgery
- Infectious Disease
- Aortic Aneurysm Management
Background:
- Infected aortic aneurysms are rare, challenging to treat, and linked to high morbidity.
- Effective management strategies and prognostic indicators require further elucidation.
Purpose of the Study:
- To review the management and outcomes of patients with infected aortic aneurysms.
- To identify clinical variables associated with poor outcomes in these patients.
Main Methods:
- Retrospective review of 43 patients treated for infected aortic aneurysms between 1976 and 2000.
- Correlation of clinical variables with aneurysm-related death and vascular complications.
Main Results:
- Operative mortality was 21%. Common complications included ischemic colitis and graft infections.
- Cumulative survival rates at 1 and 5 years were 82% and 50%, significantly lower than non-infected cohorts.
- Extensive periaortic infection, female sex, Staphylococcus aureus, rupture, and suprarenal location predicted increased mortality risk.
Conclusions:
- Infected aortic aneurysms have aggressive presentations and complicated early outcomes.
- Late outcomes are surprisingly favorable, with low graft-related complication rates similar to standard aneurysm repair.
- In situ aortic grafting is a safe and durable treatment option for most patients.
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