Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Patterned self-assembled beads in silicon channels.

H Andersson1, C Jönsson, C Moberg

  • 1Department of Signals, Sensors and Systems, Microsystem Technology Royal Institute of Technology, Stockholm, Sweden. helene.andersson@s3.kth.se

Electrophoresis
|November 10, 2001
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Feasibility and Potential Benefits of Moderate Intensity Cycling in People Living with Lower Limb Lymphedema: A Pilot Randomized Controlled Trial.

Lymphology·2025
Same author

Exploring the cessation process from adolescence to young adulthood in individuals with lived experience of nonsuicidal self-injury: a qualitative study.

Journal of adolescence·2024
Same author

Young adults looking back at their experiences of treatment and care for nonsuicidal self-injury during adolescence: a qualitative study.

Child and adolescent psychiatry and mental health·2024
Same author

Author Correction: The loss of ions from Venus through the plasma wake.

Nature·2022
Same author

Match-Fixing Causing Harm to Athletes on a COVID-19-Influenced Gambling Market: A Call for Research During the Pandemic and Beyond.

Frontiers in psychology·2021
Same author

Urinary cytokines correlate with acute kidney injury in critically ill COVID-19 patients.

Cytokine·2021
Same journal

Kinship Inferences for Second-Degree Relatives With a Combination of STRs and Microhaplotypes.

Electrophoresis·2026
Same journal

Optimisation of Electrokinetic Extraction System: Colourimetric Determination of Copper (II) in Sand Using Polymer Inclusion Membrane.

Electrophoresis·2026
Same journal

Novel Phloroglucinol Derivatives as Neuraminidase Inhibitors Identified From Humulus lupulus L. Extract by At-Line Nanofractionation Platform.

Electrophoresis·2026
Same journal

Protein-Based High-Performance Liquid Chromatography and Cyclodextrin-Capillary Electrokinetic Chromatography for the Chiral Separation of Azoles.

Electrophoresis·2026
Same journal

Dynamics of Heparin Translocations Through Solid-State Nanopores.

Electrophoresis·2026
Same journal

Production of Protein Hydrolysates and Bioactive Peptides From Lablab purpureus and Macrotyloma uniflorum via Optimized Extraction and Proteolysis Protocols.

Electrophoresis·2026
See all related articles

This study introduces a novel microfluidic technique using microcontact printing and self-assembly for selective bead trapping without physical barriers. This method precisely positions beads for advanced biochemical and organic chemistry screening and analysis.

Area of Science:

  • Microfluidics
  • Surface Chemistry
  • Biochemistry

Background:

  • Microfluidic devices are crucial for biochemical and organic chemistry analysis.
  • Existing methods for bead manipulation in microfluidics often rely on physical barriers, limiting flexibility and throughput.
  • Selective and precise bead immobilization is essential for developing advanced screening and analysis tools.

Purpose of the Study:

  • To present a novel, barrier-free technique for selective bead trapping in microfluidic devices.
  • To demonstrate the versatility of the method across different substrates (silicon, quartz, plastic).
  • To validate the stability and precision of immobilized beads under flow conditions.

Main Methods:

  • Utilizing microcontact printing to modify surface chemistry within microchannels.

Related Experiment Videos

  • Employing self-assembly principles for bead immobilization onto modified channel walls.
  • Fabricating microchannels in silicon, quartz, and plastic substrates.

    • Main Results:

    • Achieved selective immobilization of streptavidin-, amino-, and hydroxy-functionalized microspheres on silicon channel walls with good surface coverage.
    • Generated high-resolution patterns of self-assembled beads as narrow as 5 microm.
    • Confirmed bead immobilization stability under fluid flow, demonstrating robustness for applications.

    Conclusions:

    • The presented microcontact printing and self-assembly technique offers a fast, convenient, and simple method for precise bead positioning in microfluidics.
    • This barrier-free approach enhances the utility of microfluidic devices for screening and analysis in biochemistry and organic chemistry.
    • The technique's adaptability to various substrates and its demonstrated precision open new avenues for microfluidic applications.