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Real Time Measurements of Membrane Protein:Receptor Interactions Using Surface Plasmon Resonance (SPR)
Published on: November 29, 2014
[Application of surface plasmon resonance in molecular biology]
1Laboratory of Electroanalytical Chemistry, National Analytical Research Center of Electrochemistry and Spectroscopy, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, China.
Abstract:
The application of surface plasmon resonance (SPR) in molecular biology was reviewed. The biomolecular interaction can be detected with SPR in real time and in situ without the use of labels, the association and dissociation can be monitored continuously, and multi-component complex interaction can be followed step by step. The applications of the SPR in the fields of molecular biology, demonstrated the advantage of this technique that couldn't achieved by the routine techniques.

