Related Experiment Video
Updated: Jul 14, 2026

Open Tracheostomy Gastric Acid Aspiration Murine Model of Acute Lung Injury Results in Maximal Acute Nonlethal Lung Injury
Published on: February 26, 2017
Tracheoesophageal fistula and massive pneumoperitoneum after prolonged mechanical ventilation
P D Kumar1, J Rainey, B Kotton
1Department of Medicine and Surgery, Huron Hospital, Cleveland, Ohio, USA.
Abstract:
We describe a patient who had two unusual complications of prolonged mechanical ventilation-tracheoesophageal fistula and pneumoperitoneum-with a fatal outcome. Recurrent pulmonary aspirations and massive abdominal distention in the setting of longstanding artificial ventilation should alert the physician to these possibilities.
Insights
Prolonged mechanical ventilation can lead to rare complications like tracheoesophageal fistula and pneumoperitoneum. Physicians should consider these serious conditions when patients show signs of recurrent aspiration and abdominal distention.
Area of Science:
- Medicine
- Critical Care Medicine
- Pulmonology
Background:
- Mechanical ventilation is a life-support measure for respiratory failure.
- Prolonged use of mechanical ventilation can lead to various complications.
- Artificial ventilation necessitates careful monitoring for adverse events.
Observation:
- A patient developed tracheoesophageal fistula and pneumoperitoneum during prolonged mechanical ventilation.
- The patient experienced recurrent pulmonary aspirations.
- Massive abdominal distention was noted in the patient.
Findings:
- Tracheoesophageal fistula is a rare but serious complication of mechanical ventilation.
- Pneumoperitoneum can also occur as a consequence of prolonged artificial ventilation.
- These complications, though unusual, can have a fatal outcome.
Implications:
- Physicians should maintain a high index of suspicion for these complications.
- Early recognition of tracheoesophageal fistula and pneumoperitoneum is crucial.
- Awareness of these risks can improve patient management in intensive care settings.
Related Concept Videos
Pneumothorax-I
Pneumothorax can be even further classified as spontaneous, traumatic, and tension pneumothorax.
Pneumothorax-II
Clinical Manifestations:
Tracheostomy: Procedure and Tubes
Tracheostomy tubes can be made of semiflexible plastic (polyurethane or silicone), rigid plastic, or metal, and they come in...
Esophageal Perforation-I: Introduction
The location of esophageal perforation can vary, occurring anywhere along the esophagus.
Esophageal Perforation-II: Clinical Manifestations and Management
Clinical Manifestations:
Pneumothorax II: Pathophysiology

